Divigel gel 0.1% 1 g 28 pcs.

EUR 67.00

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Estradiol is the main and most active human female sex hormone.

Buy Divigel gel from Buypharmacy online


Divigel gel description

What is Divigel gel?

Divigel gel is an estrogenic preparation for external use.

Divigel gel - stimulates the development of the uterus, fallopian tubes, vagina, stroma and ducts of the mammary glands, pigmentation in the nipple and genital areas, the formation of secondary sexual characteristics of the female type, growth and closure of the epiphyses of long tubular bones.

Divigel synonyms and analogues

Other names for Divigel: estradiol, oestradiol.

Major Divigel synonyms include: OestrogelClimaraPineamin.

Divigel gel uses

What are the indications for Divigel gel use?

  • Oestrogen deficiency symptoms in natural or artificial menopause and other oestrogen-deficient states
  • Prevention of postmenopausal osteoporosis with a high risk of fracture when other medications for the prevention of osteoporosis are contraindicated or unsuitable.

Divigel gel dosage

How do I take Divigel gel and what is the drug's dosing regimen?

The usual starting dose is 1 g of gel per day, which corresponds to 1 mg of estradiol. The duration of application and the dosage are chosen by the doctor, taking into account the individual characteristics of patients (depending on the clinical condition, after 2-3 cycles the dose may be adjusted: from 0.5 g to 1.5 g of gel per day, which corresponds to 0.5 to 1.5 mg of estradiol per day).

A dose of Divigel should be applied once a day to the skin of the thighs or lower torso, changing the place of application regularly. The area of application by size is 1-2 palms. Divigel should not be applied to the mammary glands, face, genitals, and areas of skin with irritation. After applying the drug, you should wait a few minutes until the gel dries. The place of application should not be washed for one hour.

If the patient forgot to apply the gel on time, you should continue treatment as usual the next day. If the drug is used irregularly, menstrual-like uterine bleeding may occur.

Divigel gel side effects

What are the side effects of Divigel gel?

CNS and peripheral nervous system: headache, migraine, dizziness, depression, chorea.

Cardiovascular system: increased BP, thrombophlebitis.

Digestive system: nausea, vomiting, stomach cramps, flatulence, pain in epigastric region, cholestatic jaundice, cholelithiasis.

Allergic reactions: in the application site - rash, skin irritation, skin hyperemia, contact dermatitis.

Reproductive system disorders: metrorrhagia, scanty bloody discharge, increased size of uterine leiomyoma, endometrial hyperplasia (when administered without combination with progesterone), endometrial carcinoma (in women with intact uterus after menopause), ovarian sclerosis in long-term use, changes in libido.

Endocrine system: mammary glands engorgement (tension and/or increase), weight gain, decreased carbohydrate tolerance.

Metabolism: retention of sodium, calcium and water (edema) with long-term use; attacks of porphyria.

Other: visual impairment (change in curvature of the cornea), chloasma, melanoderma, vaginal candidiasis.

Divigel available forms

Dosage form: Transdermal gel.

Active ingredient: Estradiol.

Is Divigel available in the form of injections, powder or drops?

No, Divigel is available only in the form of transdermal gel.

Also available different dosage forms of Divigel for sale:

Where to buy Divigel gel online?

At Buypharmacy, you can buy Divigel gel with Worldwide Mail Shipping (delivery to USA, Canada, UK, Europe, Asia, Australia and other countries).

Research and more information on Divigel gel

  1. Estradiol Semihydrate Wikipedia Russian
  2. DivigelŪ (estradiol gel) 0.1% FDA
  3. Filing Review for DivigelŪ (estradiol gel 0.1%)
  4. Comparative efficacy and safety of estradiol transdermal preparations for the treatment of vasomotor symptoms in postmenopausal women: an indirect comparison meta-analysis


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