Groprinosin 500mg 50 tablets

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Groprinosin is an antiviral drug recommended for patients in the treatment of recurrent upper respiratory tract infections.

Buy Groprinosin 500mg from Buypharmacy online

Contents

Groprinosin 500mg description

What is Groprinosin?

Groprinosin is an antiviral medicine containing the active ingredient inosine pranobex. Groprinosin suppresses the herpes simplex virus (Herpes Simplex) that is pathogenic to humans when it affects the lips and skin of the face. It stimulates the impaired immune system. It is also used in complex therapy for recurrent infections of the upper respiratory tract.

Groprinosin is a complex drug that has immunostimulatory and antiviral properties. It helps to normalize the condition of the body during the disease, improve overall health. It has a detrimental effect on the herpes virus, measles, influenza A and B, multiviruses.

Groprinosin synonyms and analogues

Other names for Groprinosin: Isoprinosine, Inosine acedoben dimepranol, Inosine pranobex, Normamed.

What can I use to replace Groprinosine? 

When choosing a substitute, you should pay attention to special indications, age restrictions, use during pregnancy and the possibility of combining the drug with other medicines. The main Groprinosin analogues include: Isoprinosine, Normamed, Inosine pranobex.

Groprinosin 500mg uses

What are the indications for using the drug Groprinosin?

Groprinosin is prescribed to patients of different age categories for such disorders and pathologies:

  • influenza, acute respiratory infections;
  • Herpes virus type 1,2,3,4;
  • cytomegalovirus infection;
  • measles;
  • HPV;
  • adolescent sclerosing panencephalitis.

Groprinosin 500mg dosage

How do I take Groprinosin and what is the dosing regimen for the drug?

Groprinosin is intended to be taken orally. It is recommended to wash down the tablets with enough liquid. The remedy should be taken after a meal after 45-60 minutes. The dosage and duration of the course is adjusted individually, depending on the diagnosis, the age of the patient and the general state of the body.

Patients in the older age category are prescribed tablets of 6-8 pcs. per day no more than four times. Children from three years of age are prescribed depending on body weight and at a dose of 1/2 tablet per 5 kg of weight per day, but no more than four intakes. Duration of therapy from one to two weeks. The duration may be increased depending on the diagnosis and form of the pathology.

Groprinosin and COVID 19:

Is Groprinosin used in the treatment of COVID 19?

Experimental and clinical substantiation of using inosin pranobex in COVID 19

Inosin pranobex, the active ingredient of Groprinosin, is obtained by combining inosin with an accessory molecule that increases the availability of inosin to lymphocytes and enhances its immunostimulatory properties. Inosin pranobex is an antiviral drug with immunostimulatory effects. It belongs to the pharmacotherapeutic group "Systemic antiviral agent, ATX code - J 05 AX 05" and has been used since 1971 to treat cell-mediated immunodeficiency states associated with various viral infections. Inosin pranobex is registered in 62 countries under different trade names (IsoprinosineŽ, ViruxanŽ, VirimmunŽ, ImunovirŽ, DelimmunŽ), in the Russian Federation - under the name GroprinosinŽ. The drug is included in the UK National Formulary as an antiviral agent for the treatment of herpetic and papillomavirus infections. In the United Kingdom and Canada, Inosin pranobex is used to treat a potentially fatal complication of measles - slowly progressive subacute sclerosing panencephalitis; the drug slows the progression of neurological deficits and reduces mortality. In in vitro studies as well as clinical observations have demonstrated the ability of Inosin pranobex to inhibit the replication of both DNA- and RNA viruses, including Herpes simplex, adenoviruses, polioviruses, influenza A and B viruses, human papilloma viruses, rhinoviruses, ECHO, etc.The mechanism of antiviral action is to suppress viral RNA synthesis, which was demonstrated in culture studies for the influenza virus. Groprinosin prevents virus-induced immunosuppression, which contributes to the activation of cellular defense factors and the elimination of the virus from the body. Groprinosin increases the ability of T-lymphocytes to respond to antigens and produce IL-2, activates T-helpers type 1, reduces the production of pro-inflammatory cytokines (TNF, IL-1, IL-6, etc.) by monocyte-macrophages, neutrophils, lymphocytes. An important advantage of Groprinosin is a combination of non-specific antiviral and immunomodulatory action, making it effective for diseases of viral and mixed (viral-bacterial) nature. No cases of serious side effects have been registered during the long period of use of all the medicinal analogues of Pranobex inosine. It is compatible with antibiotics, interferons, antiviral agents. Groprinosin is prescribed without special immunological studies, based on clinical symptomatology and is used in patients of all age groups (children from three years). According to the results of a number of studies conducted abroad and in the Russian Federation, the therapeutic effect of GP at acute respiratory infections is established, which is characterized by: - rapid localization of the focus of infection (which in turn reduces the viral load); - reduction in the level of inflammation; - relief of the clinical course of viral diseases; - reduction in the terms of recuperation; - increased periods of remission in chronic recurrent diseases; - reduced risk of complications, the probability of reinfection and bacterial superinfection.

Thus, the combination of nonspecific antiviral and immunomodulatory effects is an important advantage of the drug Groprinosin, determining its effectiveness for diseases of viral nature.

Thus, the presented data on antiviral and immunomodulatory properties of pharmacopoeia zinc and groprinosin, their effectiveness and safety in the treatment of acute respiratory infections in patients of different ages give grounds to discuss the possibility of their use in COVID-19 for prevention and treatment.

Groprinosin 500mg side effects

What are the side effects of Groprinosin?

Side effects of the body to the remedy Groprinosin are observed when the recommendations prescribed in the instructions are not followed. Observed from the immune, nervous, digestive, urinary and musculoskeletal systems, as well as skin, liver and biliary tract, laboratory indicators. Accompanied by the corresponding symptoms, if detected, it is recommended to immediately contact a specialist for further consultation.

Groprinosin available forms

Dosage form: Tablets.

Active ingredient: Inosin pranobex

Is Groprinosine available in the form of injections, powder or drops?

Yes, Groprinosine is available in the form of tablets, each tablet contains 500 mg of the active substance and syrup.

You can also buy Groprinosin in other dosages and forms:

  • Groprinosin-Richter syrup 50 mg/ml 150 ml

If you need a different dosage, please contact us

  • Groprinosine 500 mg 20 tablets
  • Groprinosine 500 mg 30 tablets

Where to buy Groprinosin 500 mg online?

Buypharmacy offers Groprinosin 500 mg for sale with worldwide mail delivery (shipping to USA, Canada, UK, Europe, Asia, Australia and other countries).

Research and more information about Groprinosin

  1. Inosine pranobex Wikipedia
  2. Isoprinosine: an overview
  3. Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic Trial
  4. Isoprinosine for COVID 19 Treatment
  5. Inosine pranobex is safe and effective for the treatment of subjects with confirmed acute respiratory viral infections: analysis and subgroup analysis from a Phase 4, randomised, placebo-controlled, double-blind study

 


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